Background

Transcatheter Aortic Valve Implantation (TAVI) has emerged as an effective alternative to surgical aortic valve replacement in elderly patients with severe symptomatic aortic stenosis, especially those at high surgical risk.

Objective

To evaluate procedural success, safety outcomes, mortality, and functional improvement following TAVI in elderly patients.

Methods

A prospective multicenter observational study was conducted among 685 elderly patients aged ≥75 years undergoing TAVI between January 2021 and December 2024 across tertiary cardiac centers in South Asia. Clinical, echocardiographic, procedural, and 30-day outcome data were analyzed.

Results

Mean age was 81.6 ± 5.4 years. Procedural success was achieved in 96.2% of cases. Thirty-day mortality was 5.7%. Major vascular complications occurred in 6.4%, stroke in 2.6%, and permanent pacemaker implantation in 11.8%. Significant improvement was observed in mean aortic valve gradient and NYHA functional class after TAVI.

Conclusion

TAVI is a safe and effective treatment option for elderly patients with severe symptomatic aortic stenosis. The procedure provides high success rates, acceptable short-term mortality, improved hemodynamic performance, and significant functional recovery.